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簡(jiǎn)要描述:TXNIP may act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. It interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. It functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. It is req
產(chǎn)品型號(hào):bsm-54127R
廠商性質(zhì):生產(chǎn)廠家
更新時(shí)間:2025-02-27
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