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簡(jiǎn)要描述：This gene encodes a mitogen-responsive phosphoprotein. It is expressed in normal ovarian epithelial cells, but is down-regulated or absent from ovarian carcinoma cell lines, suggesting its role as a tumor suppressor. This protein binds to the SH3 domains of GRB2, an adaptor protein that couples tyrosine kinase receptors to SOS (a guanine nucleotide exchange factor for Ras), via its C-terminal proline-rich sequences, and may thus modulate growth factor/Ras pathways by competing with SOS for bin
產(chǎn)品型號(hào)：bs-5999R廠商性質(zhì)：生產(chǎn)廠家更新時(shí)間：2025-02-26訪 問(wèn) 量： 78產(chǎn)品分類
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